RESEARCH OF ANTIOXIDANT AND ANTIRADICAL ACTIVITIES IN VITRO OF EXTRACTS OF PLANTS GROWING ON THE TERRITORY OF KAZAKHSTAN

This work is devoted to the comparative study of the content of the sum of soluble polyphenolic compounds, antioxidant and antiradical activities of plant extracts growing in the territory of the Republic of Kazakhstan. In vitro experiments were carried out according to the generally accepted method for determining the total content of phenolic compounds by the Folin-Chocalteu method, the total antioxidant (reducing) activity was determined by the method of iron-reducing potential (FRAP method), antiradical activity by inhibition of the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical by the analyzed substances, using spectrophotometric analysis methods. The analysis of the totality of the data obtained allows us to place the studied extracts in the following row, depending on the number of phenolic compounds and the values of the antiradical and total antioxidant activities of the extracts: Harmala>Equisetum>Taraxacum > Liquorice.

A pronounced positive correlation was revealed between the content of phenolic compounds and all indicators of the antioxidant properties of the tested phytopreparations. Among the studied plants, extracts of Harmala and Equisetum are distinguished as demonstrating the highest total antioxidant and antiradical potential. The presented results are the basis for further more detailed study of the antioxidant, antiradical and hepatoprotective properties of herbal medicinal raw materials.